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Steroid receptor coactivator-1 is a histone acetyltransferase

 

Steroid receptor coactivator - 1 is a histone acetyltransferase

 

"Study sheds new light on tamoxifen resistance". p p a Manual assertion inferred from combination of experimental and computational evidencei 5 p This subsection of the Structure section is used to indicate the positions of experimentally determined beta strands within

 

the protein sequence. 1 p This subsection of the PTM / Processing section specifies the position and type of each modified residue excluding a a and a href help/mod_res' residuei PhosphoserineCombined sources p Manually validated information inferred from a combination of experimental and computational evidence. Ppara activates gene expression. External links edit Further reading edit Liao L, Kuang SQ, Yuan Y, Gonzalez SM, O'Malley BW, Xu J (2003). Retrieved from " ". 24:8716-8726(2004) PubMed Europe PMC Abstract Cited for: interaction with UBE2L3. Interacts with the lxxll motif of stat6. "Expression of RAC 3, a steroid hormone receptor co-activator in prostate cancer". Interacts with the FDL motif of stat5A and stat5B. p p a Manual assertion inferred from sequence similarity toi 24 Publications p Manually curated information for which there is published experimental evidence. Onate SA, Boonyaratanakornkit V, Spencer TE, Tsai SY, Tsai MJ, Edwards DP, O'Malley BW (1998). 1997 Sep 11;389(6647 194-8. Steroid receptor coactivator - 1 is a histone acetyltransferase. Spencer TE(1 Jenster G, Burcin MM, Allis CD, Zhou J, Mizzen. CA, McKenna NJ, Onate SA, Tsai SY, Tsai MJ, O Malley. Author information: ( 1)Department of Cell Biology, Baylor College of Medicine, Houston, Texas. Steroid receptor coactivator - 1 is a histone acetyltransferase, nature The Function of, steroid Receptor Coactivator - 1 in Normal Tissues

Steroid receptor coactivator-1 is a histone acetyltransferase


Nuclear receptor coactivator 1 - Wikipedia

Nuclear receptor coactivator 3 - Wikipedia

p This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes. Additionally, this section gives relevant information on each alternative protein isoform. Chen H, Lin RJ, Schiltz RL, Chakravarti D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM (1997). "BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation". I p When browsing through different UniProt proteins, you can use the basket to save them, so that you can back to find or analyse them later. P a Domainsi Domains and Repeats Feature key Position(s) DescriptionActions Graphical view Length p This subsection of the a and Domains /a section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic. Kim HJ, Yi JY, Sung HS, Moore DD, Jhun BH, Lee YC, Lee JW (Sep 1999). Wang JC, Stafford JM, Granner DK (1998). p p More information in the a evidence code guide /a /p Inferred from direct assayi nucleoplasm Source: HPA Plasma Membrane Other locations neuron projection Source: Ensembl protein complex Source: cafa p Inferred from Mutant Phenotype /p p Describes annotations that are concluded from looking. This is also the sequence that appears in the downloadable versions of the entry. Spencer TE 1, Jenster G, Burcin MM, Allis CD, Zhou J, Mizzen CA, McKenna NJ, Onate SA, Tsai SY, Tsai MJ, O'Malley. "An lxxll motif in the transactivation domain of stat6 mediates recruitment of NCoA-1/SRC-1". The available evidence indicates that acetylation of chromatin in vivo is coupled to transcription and that specific histone acetyltransferases (HATs)target histones bound to DNA and overcome the inhibitory effect of chromatin on gene expression. The steroid - receptor coactivator, sRC- 1 is a coactivator for many members. The AD1 domain is required for the recruitment of secondary coactivators, such as cAMP response element binding protein (creb)-binding protein (CBP) and the histone acetyltransferase p300 (Figure 1 ). Once SRC- 1 has complexed with its ligand-bound receptor at the DNA, it must bring in additional proteins such. The nuclear receptor coactivator 1 (ncoa1) is a transcriptional coregulatory protein that contains several nuclear receptor interacting domains and an intrinsic histone acetyltransferase activity (EC ). Steroid Receptor Coactivator 1 (SRC1)-creb Review of the in Vivo Functions of the p160

Steroid receptor coactivator-1 is a histone acetyltransferase

 

 

Ncoa1 - Nuclear receptor coactivator 1 - Homo sapiens (Human

WikiGenes - ncoa1 - nuclear receptor coactivator 1)

p p a Manual assertion inferred from combination of experimental and computational evidencei Ref.38 "Site-specific mapping of the human sumo proteome reveals co-modification with phosphorylation." Hendriks.A., Lyon., Young., Jensen.J., Vertegaal.C., Nielsen.L. p p a Manual assertion inferred from combination of experimental and computational evidencei Ref.36 "Toward a comprehensive characterization of a human cancer cell phosphoproteome." Zhou., Di Palma., Preisinger., Peng., Polat.N., Heck.J., Mohammed. P a href help/entry_history' historyi Integrated into UniProtKB/Swiss-Prot: October 11, 2004 Last sequence update: September 11, 2007 Last modified: December 20, 2017 This is version 170 of the entry and version 3 of the sequence. P a interactionsi Show more details With Entry #Exp. P a identifieri 9606 ncbi p This subsection of the Names and taxonomy section contains the taxonomic hierarchical classification lineage of the source organism. To improve security and privacy, we are moving our web pages and services from http to https. P a informationi p This subsection of the Entry information section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. P a href help/mutagen' K R: Abolishes sumoylation; when associated with R-732. Interacts with stat3 following IL-6 stimulation. p p a Manual assertion based on experiment ini Ref.17 "Phosphorylation of steroid receptor coactivator-1. Integrated resource of protein families, domains and functional sites More. 7 8, clinical significance edit, the ratio of, pAX2 to AIB-1 protein expression may be predictive of the effectiveness of tamoxifen in breast cancer treatment. Analysis of the Steroid Receptor Coactivator 1 (SRC1)-creb Binding Protein Interaction Interface and Its Importance for the Function of SRC1. In contrast, the putative histone acetyltransferase domain, the Per-Arnt-Sim basic helix-loop- helix domain, the glutamine-rich domain, and AD2 can each be removed without loss. 1 ) (reviewed in Ref.5). Anabolic Steriods - WebMD Bodybuilding Fitness Blog & Steroid Profiles, Female BES Hi-Fi Hair Color/Barva na vlasy Zucchero - Platinov

 

Steroid receptor coactivator-1 is a histone acetyltransferase

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Corresponds to variant dbSNP:rs1049016 Ensembl. Rhabdomyosarcoma is the most common soft tissue carcinoma in childhood, representing of all malignancies in children.1 Publication p Manually curated information for which there is published experimental evidence. Lee SK, Anzick SL, Choi JE, Bubendorf L, Guan XY, Jung YK, Kallioniemi OP, Kononen J, Trent JM, Azorsa D, Jhun BH, Cheong JH, Lee YC, Meltzer PS, Lee JW (Nov 1999). Puigserver P, Adelmant G, Wu Z, Fan M, Xu J, O'Malley B, Spiegelman BM (Nov 1999). P a href help/variant' variantiVAR_019772 E A 3 Publications p Manually curated information for which there is published experimental evidence. p p a Manual assertion inferred from combination of experimental and computational evidencei 3 p This subsection of the Structure section is used to indicate the positions of experimentally determined helical regions within the protein sequence. 33 34 References edit a b c GRCh38: Ensembl release 89: ensg Ensembl, May 2017 a b c GRCm38: Ensembl release 89: ensmusg Ensembl, May 2017 "Human PubMed Reference. "CBP/p300 interact with and function as transcriptional coactivators of brca1". P a href help/conflict' conflicti L R in AAB50242 (PubMed: 9575154 ).Curated 1 Natural variant Feature key Position(s) DescriptionActions Graphical view Length p This subsection of the Sequence section describes natural variant(s) of the protein sequence. P a href help/conflict' conflicti D G in AAT47737 (PubMed: ).Curated 1 p This subsection of the Sequence section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. "Differential mechanisms of nuclear receptor regulation by receptor-associated coactivator 3". P a href help/motif' lxxll motif 5 5 p This subsection of the Family and Domains section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance. Involved in the coactivation of different nuclear receptors, such as for steroids ( PGR, GR and ER retinoids (RXRs thyroid hormone (TRs) and prostanoids ( ppars). Also involved in coactivation mediated by stat3, stat5A, stat5B and stat6 transcription factors. Displays histone acetyltransferase activity toward H3 and. Culturismo, Esteroides Anabolizantes y, fitness 2009 ifbb Europa Super Show Anabolic peak vs hard mass

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